Runes grant effects and stats based on how many are equipped to a monster. You’ll get a lot of runes, and you only have so much space – so it helps to know which ones you should keep. There’s a lot of things to consider though, so here’s some things to keep in mind.
Speed is the most important stat in the game Only slot 2 runes can have a speed main stat This means that even “bad” slot 2 runes should be considered if they have speed Only slots 2/4/6 can give % stats This means that flat stats (non %) 2/4/6 runes can usually be discarded Even if a 2/4/6 is a flat stat, if it has speed, it’s worth upgrading a few times
Only Keep Purple & Gold 6* Runes
Even if you’re a new player, the game gives you enough runes to clear Giants B12, so there’s not a real need to keep every rune that might be good. Blue runes only have two substats to start off with, and they gain another at +9 and +12. This means you’re missing out on stat upgrades. Purple runes start off with 3 substats, and gold/legendary runes will have all 4 right off the bat, so they’ll generally yield more stats. The same goes for 5* runes. You can use them, but you’ll want to replace then with 6* runes later.
How To Determine if the Substats Are Worth It
Once you’ve got a high-rarity rune, you’ll want to figure out whether or not the substats are good. As a rule of thumb, these are the most desirable substats:
Speed % Crit Damage % Crit Rate % Atk % HP
For example, the rune above fits the criteria. It’s purple, and it’s a 6* rune. The good ends there. A flat HP substat is subpar at best (until the endgame), and accuracy and % Atk don’t really go well together. So despite this being a high-rarity rune, I’m going to sell this one. On the other hand, despite the substats not looking great, I’m going to keep this rune. This is because I have Feng Yan (Wind Panda Warrior) who deals damage based on how much defense he has. While you might not have a Monster capable of using a % Def rune, I do. You should consider what Monsters you have, and what Monsters you’re trying to build when looking at runes. Everything else that I got from this auto battle was either 5*, or low-rarity, so I ended up selling pretty much everything.
Sell Flat Stat 2/4/6 Runes
I mentioned before that 2/4/6 slot Runes can be % stat runes. This means that they will ALWAYS give more stats than flat stat runes. Not all 2/4/6 slot Runes will give % stats, though. For example, even though this Rune is a 5*, it has decent substats. If the main stat wasn’t flat, I’d consider upgrading it. Generally, it’s safe to sell flat-stat runes. There is an exception, though: If you get a 6* Legendary flat stat Rune that has a speed substat, it’s worth rolling. For example, while this slot 6 Rune has a flat stat, all the substat upgrades went into speed. A twenty speed substat means this rune is incredibly useful, even if it has a flat main stat. The runes (and rune quality) you need will change as you progress through the game. Although by the time you need to start changing out runes, you should have a good idea of what you need.